{"id":581,"date":"2013-05-25T18:44:06","date_gmt":"2013-05-26T01:44:06","guid":{"rendered":"http:\/\/herbalpedia.info\/Glossary\/?page_id=581"},"modified":"2013-05-25T22:16:42","modified_gmt":"2013-05-26T05:16:42","slug":"anemia-sickle-cell-falsemia","status":"publish","type":"page","link":"http:\/\/herbalpedia.info\/Glossary\/?page_id=581","title":{"rendered":"Anemia, sickle cell (Falsemia)"},"content":{"rendered":"

Anemia, sickle cell (Falsemia)<\/span><\/h2>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\n
Effect <\/span><\/h5>\n<\/td>\n
\n
Speed of <\/span><\/h5>\n
Action <\/span><\/h5>\n<\/td>\n
\n
Dose and instructions <\/span><\/h5>\n
(\u00e2\u20ac\u015300\u00e2\u20ac\u009d capsules, unless
\notherwise specified) <\/span><\/h5>\n<\/td>\n<\/tr>\n
\n

General anemia and erythrocyte benefit<\/span><\/strong><\/h4>\n<\/td>\n<\/tr>\n

\n

Dong quai root <\/span><\/p>\n<\/td>\n

\n

Moderate <\/span><\/p>\n<\/td>\n

\n

10 per day <\/span><\/p>\n<\/td>\n<\/tr>\n

\n

Bai zhi root <\/span><\/p>\n<\/td>\n

\n

Moderate <\/span><\/p>\n<\/td>\n

\n

10 per day <\/span><\/p>\n<\/td>\n<\/tr>\n

\n

Amla fruit (or, contained
\nin Triphala) <\/span><\/p>\n<\/td>\n

\n

Moderate <\/span><\/p>\n<\/td>\n

\n

10 per day <\/span><\/p>\n<\/td>\n<\/tr>\n

\n

Pipali peppercorn <\/span><\/p>\n<\/td>\n

\n

Moderate <\/span><\/p>\n<\/td>\n

\n

10 per day <\/span><\/p>\n<\/td>\n<\/tr>\n

\n

Ashwaganda root <\/span><\/p>\n<\/td>\n

\n

Moderate <\/span><\/p>\n<\/td>\n

\n

10 per day <\/span><\/p>\n<\/td>\n<\/tr>\n

\n

Wild yam root <\/span><\/p>\n<\/td>\n

\n

10 per day <\/span><\/p>\n<\/td>\n<\/tr>\n

\n

General cardiovascular system benefit <\/span><\/strong><\/h4>\n<\/td>\n<\/tr>\n

\n

Arjuna bark <\/span><\/p>\n<\/td>\n

\n

Moderate <\/span><\/p>\n<\/td>\n

\n

10 per day <\/span><\/p>\n<\/td>\n<\/tr>\n

\n

Angio-Plex (contains
\nChinese rehmannia root) <\/span><\/p>\n<\/td>\n

\n

Moderate <\/span><\/p>\n<\/td>\n

\n

10 per day <\/span><\/p>\n<\/td>\n<\/tr>\n

\n

Endoplex (contains
\nprickly ash bark) <\/span><\/p>\n<\/td>\n

\n

Prickly ash also
\nanalgesic for sickle cell patients <\/span><\/p>\n<\/td>\n

\n

5 per day <\/span><\/p>\n<\/td>\n<\/tr>\n

\n

Ginkgo Forte <\/span><\/p>\n<\/td>\n

\n

Enhance circulation <\/span><\/p>\n<\/td>\n

\n

1-4 per day as indicated <\/span><\/p>\n<\/td>\n<\/tr>\n

\n

Specific clinical benefit<\/span>
\n<\/strong><\/h4>\n<\/td>\n<\/tr>\n

\n

Prickly ash bark
\n(especially clinically effective) <\/span><\/p>\n<\/td>\n

\n

Clinical evidence for
\nreducing crisis episodes <\/span><\/p>\n<\/td>\n

\n

Up to 15 per day <\/span><\/p>\n<\/td>\n<\/tr>\n

\n

Nettle <\/span><\/p>\n<\/td>\n

\n

General cell nutrient for
\nmultiple deficiencies <\/span><\/p>\n<\/td>\n

\n

Up to 15 per day <\/span><\/p>\n<\/td>\n<\/tr>\n

\n

Schisandra berry <\/span><\/p>\n<\/td>\n

\n

General cell nutrient for
\nmultiple deficiencies <\/span><\/p>\n<\/td>\n

\n

Up to 15 per day <\/span><\/p>\n<\/td>\n<\/tr>\n

\n

Zinc <\/span><\/p>\n

(Herb Technology zinc is
\nspecially formulated to reduce nausea) <\/span><\/p>\n<\/td>\n

\n

Reduce diseased cells <\/span><\/p>\n

Promote ulcer healing <\/span><\/p>\n<\/td>\n

\n

Up to 200 mg per day as
\nneeded <\/span><\/p>\n<\/td>\n<\/tr>\n

\n

Evening Primrose Oil <\/span><\/p>\n<\/td>\n

\n

EFA source <\/span><\/p>\n

Reduce diseased cells <\/span><\/p>\n<\/td>\n

\n

2,000- 4,000 mg per day <\/span><\/p>\n<\/td>\n<\/tr>\n

\n

Riboflavin (Vitamin B2) <\/span><\/p>\n<\/td>\n

\n

Wide dose range reported
\n(50- 2,000 mg per day has been used) <\/span><\/p>\n<\/td>\n<\/tr>\n

\n

Folic acid <\/span><\/p>\n<\/td>\n

\n

Reduce homocysteine
\nlevels <\/span><\/p>\n<\/td>\n

\n

As indicated <\/span><\/p>\n<\/td>\n<\/tr>\n

\n

Vitamin B12 <\/span><\/p>\n

(Assess B12 status) <\/span><\/p>\n<\/td>\n

\n

If deficient <\/span><\/p>\n<\/td>\n

\n

As indicated (sublingual
\nor injected) <\/span><\/p>\n<\/td>\n<\/tr>\n

\n

Assess status: <\/span><\/p>\n

Carotenoids <\/span><\/p>\n

Magnesium <\/span><\/p>\n<\/td>\n

\n

As indicated <\/span><\/p>\n<\/td>\n<\/tr>\n

<\/td>\n<\/td>\n<\/td>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Notes:\u00c2\u00a0<\/span><\/h2>\n

B12:<\/span><\/h3>\n

<\/strong>Sickle cell anemia may result in vitamin B12 deficiency.<\/p>\n

    \n
  • A study of children with sickle cell anemia found them to have a higher incidence of vitamin B12 deficiency than children without the disease.<\/li>\n
  • A study of 85 adults with sickle cell anemia showed more of them had vitamin B12 deficiency than did a group of healthy people.<\/li>\n
  • A subsequent preliminary trial demonstrated that for patients with low blood levels of vitamin B12, intramuscular injections of 1 mg of vitamin B12 weekly for 12 weeks led to a significant reduction in symptoms.<\/li>\n
  • Researchers do not know whether people with sickle cell anemia who are found to be deficient in vitamin B12 would benefit equally from taking vitamin B12 supplements orally.<\/li>\n<\/ul>\n

    Folic acid and garlic:<\/span><\/h3>\n

    <\/strong>In a preliminary trial, 20 patients with sickle cell anemia were given either 1 mg of folic acid per day or folic acid plus 6 grams of aged garlic extract, 6 grams of vitamin C, and 1200 mg of vitamin E per day for six months. Patients taking the combination had a significant improvement in their hematocrit (an index of anemia) and less painful crises than those taking just folic acid.<\/p>\n

    Preliminary research has found that patients with sickle cell anemia are more likely to have elevated blood levels of homocysteine compared to healthy people. Elevated homocysteine is recognized as a risk factor for cardiovascular disease. In particular, high levels of homocysteine in sickle cell anemia patients have been associated with a higher incidence of stroke.<\/p>\n

    Deficiencies of vitamin B6, vitamin B12, and folic acid occur more frequently in people with sickle cell anemia than in others and are a cause of high homocysteine levels.<\/p>\n

    A controlled trial found homocysteine levels were reduced 53% in children with sickle cell anemia receiving a 2\u00e2\u20ac\u201c4 mg supplement of folic acid per day, depending on age, but vitamin B6 or B12 had no effect on homocysteine levels.<\/p>\n

    A double-blind trial of children with sickle cell anemia found that children given 5 mg of folic acid per day had less painful swelling of the hands and feet compared with those receiving placebo, but blood abnormalities and impaired growth rate associated with sickle cell anemia were not improved.<\/p>\n

    In the treatment of 14 \u00c2\u00a0sickle cell anemia, folic acid is typically supplemented in amounts of 1,000 mcg daily. Anyone taking this amount of folic acid should have vitamin B12 status assessed by a healthcare professional.<\/p>\n

    Iron:<\/span><\/h3>\n